Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Acetaminophen metabolism Frontiers Phytic acid attenuates acetaminophen induced hepatotoxicity via modulating iron mediated oxidative stress and SIRT 1 expression in mice Xia & He Publishing Acetaminophen Glutathione Disodium Salt CAS 64889 81 2 (free acid) SCBT Santa Cruz Biotechnology The gamma glutamyl pathway after glutathione depletion due to Download Scientific Diagram